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Understanding Sildenafil
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What is Sildenafil?
Sildenafil, known as the generic form of Viagra, is a prescription medication designed primarily to manage male sexual dysfunction, often referred to as impotence or erectile dysfunction (ED). This medication is typically administered in tablet form and is recommended to be taken in anticipation of sexual activity, though it should not be used more than once within a 24-hour timeframe. Additionally, sildenafil is utilized in different formulations to treat pulmonary arterial hypertension (PAH), a condition that affects blood pressure in the arteries leading to the lungs, applicable to both men and women. It's crucial to note that these diverse formulations should not be combined or used interchangeably.
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How does sildenafil work?
Sildenafil functions as a phosphodiesterase type 5 (PDE-5) inhibitor, which means it impedes the degradation of cyclic guanosine monophosphate (cGMP), a molecule that relaxes blood vessels. With the right level of sexual stimulation, sildenafil enhances blood flow to the penis, facilitating not just the achievement but also the maintenance of an erection. It’s important to understand that sildenafil alone is not effective without sexual arousal, as its mechanism relies heavily on stimulation.
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How to take sildenafil for best results
For optimal results, sildenafil should ideally be ingested about one hour before engaging in sexual activity; however, it may be effective when taken anywhere from 30 minutes to four hours beforehand. Users are advised to take sildenafil as needed, but without exceeding the maximum recommendation of once per day. Importantly, sildenafil can be consumed with or without meals, offering flexibility in its administration.
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How long does sildenafil take to work?
The effectiveness of sildenafil in improving erectile dysfunction is contingent upon sexual stimulation. Typically, users can expect the medication to begin working within approximately 60 minutes of ingestion, making it essential to plan ahead for sexual activity.
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How long does sildenafil last?
Users may find that the effects of sildenafil can last anywhere from two to four hours, providing a window of time for sexual activity. It is critical to seek immediate medical attention if an erection persists beyond four hours, as this condition can lead to serious complications.
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What are the side effects of sildenafil?
Like any pharmaceutical treatment, sildenafil can produce side effects, some of which may be serious. Common side effects associated with sildenafil include headaches, flushing (which may manifest as warmth and redness typically affecting the face, neck, and chest), nasal congestion, and indigestion. These effects are generally transient and subside once the medication is metabolized. Should side effects become problematic or persistent, it is advisable to consult with your healthcare provider.
In rare cases, serious side effects may arise, warranting immediate medical attention. These include sudden changes in hearing or vision, an abrupt drop in blood pressure, or priapism (an erection lasting more than four hours). Additionally, some rare but severe ocular issues have been reported, potentially leading to changes in eyesight, including temporary or, in some instances, permanent vision loss. Those with pre-existing heart conditions may be at increased risk for cardiovascular events such as arrhythmias, heart attacks, or strokes when taking sildenafil. It is imperative to disclose your complete medical history to your Walgreens healthcare provider to ascertain the safety of sildenafil for your use.
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How to get sildenafil for erectile dysfunction through Walgreens Virtual Care
During a consultation with a Walgreens Virtual Healthcare provider, your symptoms will be evaluated to determine the most suitable treatment options. This includes assessing whether sildenafil is appropriate for your condition and health profile.
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Frequently Asked Questions
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Is sildenafil available over the counter?
No, sildenafil cannot be purchased without a prescription from a licensed healthcare provider.
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Do you need a prescription for sildenafil?
Yes, a valid prescription is required to obtain sildenafil, as it is not sold over the counter.
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What drugs interact with sildenafil?
Numerous drug interactions can affect how well your medications perform and can amplify adverse effects. Sildenafil may interact with various medications, including certain over-the-counter products, vitamins, and supplements. Prior to commencing treatment with sildenafil, it’s crucial to discuss all medications you currently take with your Walgreens healthcare provider and pharmacist to avoid potential interactions.
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What are the differences between sildenafil and Viagra?
Sildenafil is the generic version of Viagra. Both share identical active ingredients and are prescribed for the treatment of erectile dysfunction.
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Will insurance cover a sildenafil prescription?
Some insurance plans may cover sildenafil prescribed for erectile dysfunction. It is advisable to verify coverage with your insurance provider to understand if sildenafil is included in your policy.
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Does Walgreens offer the brand Viagra?
Yes, Walgreens Virtual Care provides both the brand-name Viagra as well as the generic variant, sildenafil, to effectively address erectile dysfunction. Consult with your healthcare provider to determine the most suitable option for your needs.
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Can sildenafil be taken with food or alcohol?
Sildenafil is safe to take with or without food. However, it is advised to limit or avoid alcohol consumption while using sildenafil, as alcohol may heighten the risk of low blood pressure.
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Sildenafil vs. tadalafil: What’s the difference?
Both sildenafil (generic for Viagra) and tadalafil (generic for Cialis) are PDE-5 inhibitors used to treat erectile dysfunction. Both medications should be taken at least 30 minutes prior to sexual activity and can be taken as needed; however, tadalafil may have a longer duration of action than sildenafil, which can lead to alternative dosing strategies that can be taken every day, regardless of sexual activity. It’s important to consult your healthcare provider when deciding which medication best fits your individual circumstances.
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Sildenafil vs. Vardenafil: What’s the difference?
Sildenafil and vardenafil (generic for Levitra) are both PDE-5 inhibitors that function similarly to treat erectile dysfunction. While vardenafil is suggested to be taken one hour prior to sexual activity, sildenafil can be administered as soon as 30 minutes and up to four hours before sexual activity. Both last approximately the same duration, and neither should be taken more than once every 24 hours. For safety and efficacy, consult your healthcare provider for guidance on which medication is more suitable for your situation.
References
1. Viagra (sildenafil citrate) tablets, for oral use. Package insert. Pfizer Labs. 2014.
2. Sildenafil: MedlinePlus drug information. MedlinePlus. Accessed February 19, 2025.
3. Cialis (tadalafil) tablets, or oral use. Package insert. Eli Lilly and Company. 2011.
4. Levitra (vardenafil hydrochloride) tablets, for oral use. Package insert. Bayer HealthCare Pharmaceuticals Inc. 2014
Disclaimers
*Currently available in the following states: AL, AZ, CA, CO, CT, FL, GA, IL, IN, KS, KY, LA, MA, MD, MI, MN, MO, NC, NJ, NV, NY, OH, OK, PA, SC, TN, TX, VA, WA, WI
Based on national averages. Actual times may vary.
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Prescription based on medical evaluation and not guaranteed.
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