Tadalafil Tablets 20mg: Uses, Side Effects, Interactions, Warnings, and Dosing
Tadalafil Tablets 20mg
What is Tadalafil used for?
Tadalafil is a phosphodiesterase-5 (PDE5) inhibitor, primarily prescribed for several conditions, including:
- Erectile Dysfunction (ED): This condition results in difficulty achieving or maintaining an erection, impacting sexual performance and satisfaction.
- Pulmonary Arterial Hypertension (PAH): A serious condition characterized by high blood pressure in the lungs' arteries, leading to heart complications.
- Benign Prostatic Hyperplasia (BPH): An enlargement of the prostate gland that can cause urinary tract issues, including frequency and urgency.
Beyond these primary uses, Tadalafil may be utilized for other medical conditions as determined by a healthcare provider based on individual needs and assessments.
How does Tadalafil work (mechanism of action)?
Tadalafil works by inhibiting the enzyme phosphodiesterase-5 (PDE5), which leads to increased levels of cyclic guanosine monophosphate (cGMP), promoting the relaxation of smooth muscle tissue in blood vessels. This mechanism results in enhanced blood flow to targeted areas:
- For erectile dysfunction, Tadalafil increases blood flow to the penis during sexual arousal, facilitating an erection.
- For pulmonary arterial hypertension, it relaxes the pulmonary arteries, helping to reduce blood pressure and relieve the heart's workload.
- For benign prostatic hyperplasia, it relaxes the muscles in the bladder and prostate, improving symptoms such as urinary urgency.
How is Tadalafil supplied (dosage forms)?
Tadalafil is available in various formulations and strengths. Common brand names include:
- Adcirca
- Cialis
- Alyq
- Tadliq
The available dosage forms include:
- 2.5 mg oral tablets
- 5 mg oral tablets
- 10 mg oral tablets
- 20 mg oral tablets
How should I store Tadalafil?
Tadalafil should be kept at room temperature, ideally between 68°F to 77°F (20°C to 25°C). It is acceptable for short periods to be stored between 59°F to 86°F (15°C to 30°C), but it is crucial to place it in a cool, dry location away from moisture.
Side Effects
What are the most common side effects of Tadalafil?
Tadalafil usage may lead to a variety of common side effects, including:
- Headache
- Flushing or redness of the skin
- Indigestion or stomach upset
- Nasal congestion or stuffy nose
- Muscle or back pain
- Nausea or feelings of sickness
- Dizziness or light-headedness
Should these side effects become persistent or bothersome, please inform your healthcare provider.
What are the serious side effects of Tadalafil?
Though serious side effects are rare, they can occur. Report any abnormal symptoms to a healthcare professional:
- Severe Allergic Reactions: Symptoms may include difficulty breathing, hives, swelling of the face, lips, tongue, or throat.
- Priapism: A prolonged and painful erection lasting more than 4 hours; immediate medical attention is essential.
- Hypotension: Signs may include fainting, dizziness, or light-headedness.
- Vision Problems: This can range from temporary vision changes to sudden loss of vision, which warrants immediate medical advice.
- Hearing Impairment: Sudden decrease or loss of hearing requires prompt reporting to a healthcare provider.
Warnings & Precautions
Who should not use Tadalafil?
Tadalafil should be avoided by individuals who have known allergies to this medication or its components. Prior to starting treatment, healthcare practitioners should be informed about:
- All medications currently taken, including over-the-counter drugs and herbal remedies.
- History of cardiovascular conditions, including heart disease, stroke, or low blood pressure.
- Existing liver or kidney disorders, as well as blood-related conditions.
- Previous serious eye disorders or conditions affecting vision.
What should I know about Tadalafil before using it?
Before taking Tadalafil, ensure that it is prescribed by a qualified healthcare provider. Adhere to the following guidelines:
- Do not exceed the prescribed dosage without approval from your healthcare provider.
- Discuss all medications you are currently using with your doctor.
- Keep Tadalafil out of reach of children and pets to avoid accidental ingestion.
- Understand that Tadalafil does not provide protection against sexually transmitted diseases.
What should I tell my healthcare provider before using Tadalafil?
Disclose all medical conditions and medications to ensure Tadalafil is safe for you. Important points include:
- Your history with heart issues or blood pressure problems.
- Whether you have experienced any significant health events or changes.
- Any conditions that could affect the drug's efficacy or safety.
Interactions
Does Tadalafil interact with foods or drinks?
Patients taking Tadalafil should limit or avoid grapefruit products as they may increase Tadalafil levels in the bloodstream, leading to heightened side effects. Alcohol consumption should also be moderated due to its potential to exacerbate side effects.
Does Tadalafil interact with other medications?
Notify your healthcare provider about all medications you are taking, especially:
- Nitrates (e.g., nitroglycerin) – used for heart conditions.
- Guanylate cyclase stimulators (e.g., riociguat).
- Other PDE-5 inhibitors (e.g., sildenafil).
Ensuring your healthcare provider is aware of your complete medication list is essential to prevent serious drug interactions.
Overdose/Missed Dose
What should I do if I accidentally use too much Tadalafil?
If you suspect an overdose, seek immediate medical assistance or contact a Poison Control center. Be aware of overdose symptoms that may require urgent care.
What should I do if I miss a dose of Tadalafil?
If you forget to take a dose, take it as soon as you remember. If it’s close to the time for your next scheduled dose, skip the missed dose; do not double up to compensate.