Tadalafil (Cialis) is primarily used to treat erectile dysfunction (ED), which is the inability to obtain or maintain an erection sufficient for satisfactory sexual performance. This condition affects many men at different stages of their lives, and Tadalafil provides a remedy by enhancing blood flow to the penis during sexual stimulation, making it possible to achieve an erection. Additionally, Tadalafil is effective for alleviating symptoms related to benign prostatic hyperplasia (BPH), a condition characterized by an enlarged prostate. Symptoms of BPH in adult males can include difficulty in urination, such as hesitancy, dribbling, weak urinary stream, incomplete bladder emptying, painful urination, as well as increased urinary frequency and urgency.
Moreover, Tadalafil is also prescribed under the name Adcirca to improve exercise capacity in adults diagnosed with pulmonary arterial hypertension (PAH). PAH is a serious condition marked by high blood pressure in the blood vessels that supply the lungs, resulting in symptoms such as shortness of breath, dizziness, and fatigue during physical activity. Tadalafil acts by relaxing the blood vessels in the lungs, facilitating smoother blood flow and enhancing exercise ability.
It's crucial to understand that Tadalafil does not cure erectile dysfunction nor does it inherently increase sexual desire. It also does not offer protection against pregnancy or sexually transmitted infections, including HIV. Consequently, individuals should take these factors into account when considering their treatment options.
Tadalafil is available in tablet form, designed for oral administration, which means it can be taken either with food or on an empty stomach. However, it is advisable to note that taking Tadalafil with a heavy meal may delay its effects. For erectile dysfunction, there are two dosing strategies, which can be tailored to the individual's needs: taking it as needed prior to sexual activity or as a daily regimen. The 'as needed' dosage typically requires consumption at least 30 minutes before anticipated sexual activity, and cannot be taken more than once daily. On the other hand, if taken daily, patients have the flexibility to engage in sexual activity at any time without concern for timing their dose. It is imperative to adhere to the prescribed dosage and frequency closely, as outlined by your healthcare provider.
In terms of treatment for PAH or BPH, patients are commonly instructed to take Tadalafil once daily. For this regimen, all tablets for the daily dose should be taken simultaneously, without dividing them into smaller doses. Consistency is key; intake should ideally occur around the same time each day. If current medications for BPH are being used, healthcare providers may recommend discontinuing these other medications prior to starting Tadalafil. It is essential to follow your physician's instructions meticulously and to voice any uncertainties about dosing or timing.
For those using Tadalafil to address erectile dysfunction, healthcare providers generally begin treatment with a standard dose, adjusting as necessary based on how well the patient responds. Patients are encouraged to communicate openly with their doctors if they feel that the medication is not effective or if they observe any side effects. Similarly, for individuals managing PAH, it should be noted that while Tadalafil can manage this condition, it does not provide a cure. Therefore, treatment should be ongoing, even if symptoms improve, and it is critical to consult with a healthcare professional before making any changes to the treatment plan.
Patients can request a copy of the manufacturer's patient information from their pharmacist or healthcare provider to gain further insights into Tadalafil's use and considerations.
This medication is sometimes utilized for additional conditions beyond those specifically mentioned; consulting your doctor or pharmacist may provide more detailed information regarding these other potential uses.
Before taking Tadalafil
- Disclose any known allergies to Tadalafil or other medications to your healthcare provider. A comprehensive list of ingredients in Tadalafil tablets can be obtained from your pharmacist.
- Inform your physician if you are currently taking or have recently utilized any nitrates, including but not limited to riociguat (Adempas), isosorbide dinitrate (Isordil), isosorbide mononitrate (Monoket), and nitroglycerin (Minitran, Nitro-Dur, Nitromist, Nitrostat, etc.), as the interaction with Tadalafil may lead to potentially serious adverse effects.
- If you’re using illegal drugs that contain nitrates, such as 'poppers' (amyl nitrate, butyl nitrate), be sure to inform your doctor, as it could elevate the risk of complications.
- It’s critical to note that Tadalafil is marketed under various brand names, including Cialis and Adcirca, and you should only be treated with one of these formulations at any given time to avoid risk of overdose.
- Keep your doctor informed about all medications you are currently taking, whether prescribed, over-the-counter, vitamins, or dietary supplements, as many drugs can interact with Tadalafil. Mention specifically: alpha blockers (e.g., alfuzosin, doxazosin, prazosin), antifungals (fluconazole, ketoconazole), and blood pressure medications, among others. Your physician may need to adjust dosages accordingly.
- Herbal remedies, particularly St. John's Wort, should also be mentioned during your medical consultation.
- Discuss lifestyle factors such as smoking or recent dehydration symptoms (from diarrhea, vomiting, or excessive sweating) with your doctor, as these can affect treatment efficacy and safety.
- For women using Tadalafil for PAH, it’s vital to notify your physician if you are pregnant, planning to become pregnant, or breastfeeding, since the implications for fetal health are not fully understood.
- Notify your healthcare providers about your Tadalafil usage prior to any surgical procedures, including dental operations.
- Moreover, talk to your doctor regarding the safe consumption of alcohol during Tadalafil therapy. Excessive alcohol intake can exacerbate potential side effects, particularly those relating to blood pressure.
- For men with a history of cardiovascular problems, it is important to inform your doctor if you have been advised to avoid sexual activity or if you have experienced chest pain while engaging in sexual activities.
- Finally, when receiving emergency medical care, ensure all healthcare providers know about your Tadalafil use, especially if cardiovascular issues arise.
It is advisable to have a discussion with your physician about the implications of consuming grapefruit juice during your Tadalafil treatment as it may influence the effectiveness of the medication.
If you are using Tadalafil regularly for erectile dysfunction and miss a dose, take the missed dose as soon as you remember. However, if your next scheduled dose is imminent, skip the missed dose entirely and continue with your regular dosing schedule without doubling the amount.
For patients on Tadalafil for PAH or BPH, the same principle applies: take the missed dose when recalled unless it is nearing the next scheduled intake time, in which case you should skip it and not double up on the dosage.
Tadalafil may cause side effects. Inform your doctor if any of these symptoms are severe or do not go away:
- Headache
- Indigestion or heartburn
- Nausea
- Diarrhea
- Flushing of the skin
- Muscle and back pain
- Cough
Serious side effects can occur. If you experience any of the following, seek medical attention immediately:
- Sudden decrease or loss of vision
- Blurred vision or changes in color perception
- Sudden decrease or loss of hearing
- Tinnitus or ringing in the ears
- An erection lasting more than 4 hours (priapism)
- Symptoms of a heart attack or stroke, including chest pain and dizziness
- Severe allergic reactions such as hives or difficulty breathing
- Swelling in the face or limbs
- Skin rashes or unusual peeling
Reports of sudden vision loss have been noted in patients after taking Tadalafil or similar medications, with some experiencing permanent damage. If sudden vision changes occur, immediate medical care is paramount.
Similar concerns exist for sudden hearing loss, often occurring in one ear. If accompanying symptoms like dizziness or tinnitus appear, urgently contact your healthcare provider to discuss further treatment.
In addition, patients can experience an array of other side effects. Should you notice anything unexpected while on Tadalafil, it is essential to report it to your healthcare provider.
If severe side effects manifest, they can be reported to the FDA's MedWatch program via their website or by calling their helpline.
To ensure efective preservation of Tadalafil, retain this medication in its original, tightly sealed package and keep it away from children's reach. Store it at room temperature, avoiding excessive moisture or heat, especially areas like bathrooms.
Unused medications require careful disposal. Do not dispose of medications in the toilet, instead choose proper disposal methods such as drug take-back programs. Consult your pharmacist or local waste facility for community options. More information on safe medication disposal can be found on the FDA website.
Children's safety is a priority: make sure all medications are stored securely and out of sight as many containers are not childproof. Always utilize safety caps and put away medications in a high and secure place.
If an overdose occurs, immediately contact the local poison control center. For emergencies involving severe effects, such as loss of consciousness, or trouble breathing, call 911.
Attend all follow-up appointments with your healthcare provider to monitor your condition and response to Tadalafil.
Do not share your medication with anyone else; each prescription is tailored specifically for you. Should you have any questions regarding refills, contact your pharmacist for guidance.
Maintain a written record of all medications you're currently using, including prescriptions, over-the-counter drugs, vitamins, and supplements. This list is vital for every doctor's visit and in emergency situations.
- Adcirca®
- Cialis®
- Entadfi® (a combination product containing finasteride and tadalafil)