Frequently asked questions about Tadalafil
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Tadalafil (Cialis) is a medication primarily used to treat erectile dysfunction (ED, impotence; inability to achieve or maintain an erection) and also addresses benign prostatic hyperplasia (BPH; an enlarged prostate) symptoms, including challenges with urination such as hesitation, dribbling, weak stream, and feeling of incomplete bladder emptying. Additionally, it can cause uncomfortable symptoms like painful urination, increased urinary frequency, and urgency for adult males. On the other hand, tadalafil (Adcirca) is prescribed to enhance exercise capability in individuals dealing with pulmonary arterial hypertension (PAH; a condition marked by high blood pressure in blood vessels leading to the lungs, which may result in shortness of breath, dizziness, and fatigue). Tadalafil belongs to a category of medications known as phosphodiesterase (PDE) inhibitors. It effectively boosts erectile function by facilitating increased blood flow to the penis when sexual stimulation occurs. Such enhanced blood flow is crucial for achieving an erection.
It is important to note that tadalafil does not cure erectile dysfunction, nor does it enhance sexual desire. Furthermore, tadalafil is not designed to prevent pregnancy or the transmission of sexually transmitted infections, including human immunodeficiency virus (HIV).
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Tadalafil is available as a tablet that can be taken orally. It’s worth mentioning that it can be consumed either with or without food, providing flexibility based on personal preference. If you are prescribed tadalafil for erectile dysfunction, it is essential to adhere to your doctor's recommendations and the specific guidelines provided in this paragraph. There are two main ways to utilize tadalafil: on a daily basis or as needed. Consult with your healthcare provider to determine which dosing regimen is most appropriate for your situation. When taken as needed, tadalafil is typically ingested at least 30 minutes prior to anticipated sexual activity, ensuring it is not used more frequently than once every 24 hours. Your healthcare provider will assist in determining the optimal timing for you to take tadalafil before sexual encounters. Alternatively, tadalafil can also be taken once daily, regardless of sexual activity timing; this allows you to engage in sexual activity at any point between doses. For those on a regular dosing schedule, it’s advisable to take it at approximately the same time daily. If you have underlying health issues or are on other medications, your doctor may recommend less frequent dosing or a reduced daily dose. Always follow the instructions on your prescription label meticulously, and don’t hesitate to seek clarification from your doctor or pharmacist regarding any aspects that remain unclear. It is vital to take tadalafil precisely as prescribed—do not exceed or reduce the prescribed amounts or frequency of intake.
In instances where tadalafil is prescribed for erectile dysfunction, your physician will likely initiate treatment with a standard dose, adjusting it up or down based on your response to the medication. If you find that tadalafil is not yielding the expected results or if you encounter side effects, promptly inform your healthcare provider.
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Prior to starting tadalafil,
make sure to inform your doctor or pharmacist if you have any allergies to tadalafil, other medications, or any of the constituents present in tadalafil tablets. If in doubt, request your pharmacist for a comprehensive list of ingredients contained in the medication.
advise your doctor if you are currently taking or have recently taken certain medications like riociguat (Adempas) or nitrates such as isosorbide dinitrate (Isordil), isosorbide mononitrate (Monoket), and nitroglycerin (Minitran, Nitro-Dur, Nitromist, Nitrostat, among others). Nitrates can come in various forms, including tablets, sublingual variations, sprays, patches, pastes, and ointments. If you are unsure whether any of your medications contain nitrates, it is crucial to discuss this with your healthcare provider. Typically, your doctor will advise against tadalafil if you are on nitrates.
let your doctor know if you are using recreational drugs that contain nitrates ("poppers") like amyl nitrate, butyl nitrate, or nitrite while under tadalafil treatment. Your doctor will likely discourage the use of tadalafil in conjunction with such substances.
it's important to be aware that tadalafil is marketed under the brand names Adcirca and Cialis. You should only be on one brand at any given time.
be sure to inform your doctor and pharmacist about any other prescription or nonprescription medications, vitamins, or nutritional supplements you are taking or intend to take. Specifically mention medications such as alpha blockers (like alfuzosin, doxazosin, dutasteride, prazosin, silodosin, tamsulosin, and terazosin), amiodarone, certain antifungals (like fluconazole, griseofulvin, itraconazole, ketoconazole, and voriconazole), aprepitant, bosentan, carbamazepine, clarithromycin, diltiazem, efavirenz, erythromycin, various HIV protease inhibitors (such as indinavir, nelfinavir, and ritonavir), lovastatin, medications for hypertension, nefazodone, nevirapine, any other treatments for ED or PAH, phenobarbital, phenytoin, rifabutin, rifampin, sertraline, telithromycin, and verapamil. Your healthcare provider may need to modify the dosing of your medications or closely monitor you for any potential side effects.
notify your healthcare provider about any herbal products you are using, particularly St. John’s wort.
disclose if you are a smoker, or if you have ever experienced an erection lasting beyond 4 hours; and inform your physician if you have faced gastrointestinal issues like diarrhea or vomiting, dehydration due to inadequate fluid intake, or excessive sweating. Additionally, inform your doctor if you have or have ever had pulmonary veno-occlusive disease (PVOD), any anatomical conditions affecting the penis shape, diabetes, high cholesterol, blood pressure irregularities, heart problems such as heart attacks, angina, or heart failure, strokes, ulcers in the stomach, blood disorders, or diseases concerning blood cell function like sickle cell anemia, multiple myeloma, or leukemia. Be aware of any family history regarding eye diseases like retinitis pigmentosa or prior incidents of abrupt vision loss, especially attributed to blocked blood flow to the optic nerves.
if you're scheduled for surgery—including dental procedures—inform your surgeon or dentist that you are currently on tadalafil.
discuss with your healthcare provider the safe consumption of alcoholic beverages while undergoing treatment with tadalafil. Consuming excessive amounts of alcohol (more than five glasses of wine or five shots of whiskey) while on tadalafil can elevate the likelihood of experiencing side effects such as dizziness, headaches, rapid heart rate, and low blood pressure.
if you are using tadalafil for erectile dysfunction, inform your doctor if you’ve ever been cautioned by a healthcare professional against sexual activity for medical reasons or if you have ever experienced chest pain during sexual activity. Engaging in sexual activity may exert additional stress on your heart, especially if you suffer from heart disease. If you experience symptoms such as chest pain, dizziness, or nausea during sexual activity, seek immediate medical assistance and refrain from sexual activity until your doctor gives you the go-ahead.
make sure all your healthcare providers are aware that you are using tadalafil. In the event of an emergency medical situation regarding heart issues, healthcare professionals attending to you will need to know when you last took tadalafil.
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Consult with your healthcare provider regarding the consumption of grapefruit and grapefruit juice while on this medication, as there could be interactions.
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For those taking tadalafil for erectile dysfunction as part of a consistent regimen, if you happen to miss a dose, take it as soon as you remember. However, if the time for your next dose is approaching, skip the missed dose and continue your regular schedule. Never take a double dose or exceed one dose per day to compensate for the missed one.
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Tadalafil may cause side effects. Should you experience any of the following symptoms, make sure to inform your healthcare provider, especially if they are severe or persistent:
headaches
indigestion or heartburn
nausea
diarrhea
flushing
muscle pain or discomfort in the stomach, back, arms, legs
cough
Some adverse effects may be serious. If you encounter any of these symptoms, seek immediate medical attention:
sudden vision loss or reduction (further information below)
blurred vision
color vision changes (like seeing a blue tint on objects or having trouble distinguishing between blue and green)
abrupt hearing loss or decrease (further information below)
ringing in your ears
erection lasting longer than 4 hours
dizziness
chest pain
hives or rashes
respiratory issues or difficulties with swallowing
facial, throat, tongue, lips, eyes, hands, feet, ankles, or lower leg swelling
skin blistering or peeling
Some patients have reported experiencing a sudden loss of some or all of their vision post-administration of tadalafil or similar medications, with such vision loss being irreversible in certain instances. The precise correlation of vision loss to the medication remains unidentified. Should you experience sudden vision loss while taking tadalafil, contact your healthcare provider or seek emergency care right away. Refrain from taking any further doses of tadalafil or comparable drugs like sildenafil (Revatio, Viagra) or vardenafil (Levitra) until you've consulted with your doctor.
Meanwhile, some individuals reported abrupt hearing loss after administration of tadalafil or other similar medications. This hearing impairment typically affected just one ear and may not have improved even after stopping the medication. The exact link between hearing loss and the medication remains unclear. If you notice sudden hearing loss, often accompanying ringing in the ears or dizziness while taking tadalafil, contact your physician immediately. Avoid taking additional doses of tadalafil or related medications until you have conferred with your doctor.
Other side effects may occur while you are on tadalafil. If you face any unusual problems while using this medication, reach out to your doctor.
In case of any severe side effect, you or your healthcare provider may report it to the FDA's MedWatch Adverse Event Reporting program either online or via phone.
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Store this medication in the original container, ensuring it is tightly sealed and kept away from children. Keep it at room temperature and away from excessive heat and moisture; do not store it in the bathroom.
Unused medications should be disposed of in ways that prevent children, pets, and others from consuming them. Do not flush this medication down the toilet. The optimal way to discard your medication is through a take-back program. Consult your pharmacist or local waste management department for information regarding available take-back programs in your area. For added guidance on safe disposal, refer to the FDA's Safe Disposal of Medicines website.
It is crucial to keep all medications out of children's reach and sight since many containers, like weekly pill organizers and those for creams, eye drops, and inhalers, may not be child-resistant. To safeguard children against potential poisoning, always secure safety caps, and place medications in a location that is out of their reach or sight.
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If an overdose occurs, contact the poison control hotline immediately. You can reach them at 1-800-222-1222 or explore their online resources for more information. In cases where the individual has fainted, suffered a seizure, has difficulty breathing, or cannot be roused, promptly call emergency services at 911.
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Ensure that you keep all scheduled appointments with your healthcare provider.
It’s imperative that you do not share your medication with anyone else. If you have any questions regarding refilling your prescription, be sure to consult your pharmacist.
It's also important to maintain a documented list of all prescription and nonprescription medications you are currently taking, in addition to any vitamins, minerals, or dietary supplements. Bring this list with you whenever you have a doctor's appointment or if you are hospitalized. This information is vital to carry with you in case of emergencies.
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Adcirca®
Cialis®
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