Sildenafil

Sildenafil 25mg Tablet: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing

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What is Sildenafil 25mg used for?

Sildenafil 25mg is primarily used for the treatment of the following conditions:

  • Erectile dysfunction, a medical condition where an individual cannot achieve or maintain an erection sufficient for satisfactory sexual performance.
  • Pulmonary arterial hypertension, which refers to high blood pressure in the pulmonary arteries, affecting the lungs and the right side of the heart, leading to serious health issues.

In certain instances, Sildenafil may also be prescribed for other medical issues as determined by your healthcare provider, underscoring its versatility in treatment.

How does Sildenafil work (mechanism of action)?

Sildenafil operates by inhibiting the enzyme phosphodiesterase type 5 (PDE5), which leads to relaxation of blood vessels. The enhanced blood flow facilitates an erection when a man is sexually stimulated. For pulmonary arterial hypertension, Sildenafil assists in dilating blood vessels in the lungs, effectively lowering blood pressure and easing the heart's workload.

How is Sildenafil supplied (dosage forms)?

Sildenafil is offered under various brand names, allowing for patient choice:

  • Viagra
  • Revatio

The medication is available in several dosage forms, including:

  • 25 mg, 50 mg, and 100 mg oral tablets

How should I store Sildenafil?

Oral Tablets: Store Sildenafil oral tablets at room temperature, ideally between 68°F to 77°F (20°C to 25°C). While they can tolerate short-term exposure to lower or higher temperatures, keeping them in a cool, dry environment is optimal to maintain their effectiveness.

What are the side effects of Sildenafil?

Common Side Effects

What are the most common side effects of Sildenafil?

Patients frequently report the following side effects:

  • Headache
  • Flushing of the skin
  • Upset stomach or dyspepsia
  • Changes in vision, such as increased sensitivity to light
  • Nasal congestion or sinus pressure
  • Muscle aches and pains
  • Nausea or gastrointestinal discomfort
  • Dizziness, especially upon standing

Serious Side Effects

Though rare, some serious side effects can occur:

  • Severe allergic reactions, which may manifest as rashes, itching, or swelling
  • Priapism, a condition characterized by a painful, prolonged erection lasting longer than 4 hours
  • Sudden loss of vision, which may be irreversible
  • Loss of hearing, sometimes accompanied by tinnitus and dizziness

If any severe side effects occur, contact your healthcare provider without delay for appropriate intervention.

Warnings & Precautions

Who should avoid using Sildenafil?

Individuals with known allergies to any of the medication's ingredients or those currently on nitrates (such as nitroglycerin) should refrain from using Sildenafil due to potential adverse reactions.

It’s essential to discuss with your healthcare provider if you have a history of heart disease, low blood pressure, or other medical conditions that could complicate the use of Sildenafil.

Interactions

Are there any food or drink interactions with Sildenafil?

Consumption of a high-fat meal may delay the onset of Sildenafil's effects. Furthermore, grapefruit and grapefruit juice should be avoided, as they can lead to increased levels of Sildenafil in the bloodstream, heightening the risk of side effects.

What about interactions with other medications?

Always provide your healthcare provider with a complete list of medications you are currently taking, including over-the-counter products and herbal supplements, to prevent any harmful interactions. Noteworthy drug interactions include:

  • Nitrates, including nitroglycerin
  • Guanylate cyclase stimulators such as riociguat
  • Alpha-blockers, often used for high blood pressure

What should I do if I miss a dose or overdose?

If you miss a dose: For erectile dysfunction, Sildenafil is typically taken on an as-needed basis, negating concerns about missed doses.

If you overdose: Seek immediate medical assistance or contact a Poison Control center without delay to avoid potential complications.

What to know before taking Sildenafil?

Before initiating treatment with Sildenafil, consult with your healthcare provider for a comprehensive evaluation, particularly if you have existing health conditions. Discuss any recent surgeries, current medications, or notable changes in health status.

Conclusion

Sildenafil 25mg tablets represent a reliable treatment option for erectile dysfunction and pulmonary arterial hypertension. However, it is crucial to take them under the close supervision of a healthcare provider to ensure both safety and effectiveness. Always engage in open discussions about potential risks, side effects, and possible interactions with your healthcare provider before commencing treatment.