Sildenafil

How and when to take sildenafil

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It’s important to take sildenafil as advised by a doctor or pharmacist. Taking it correctly can aid in achieving the desired therapeutic outcomes, particularly in cases of erectile dysfunction or pulmonary hypertension.

Dosage and Strength for Erectile Dysfunction

Sildenafil tablets for erectile dysfunction are available in several strengths, including 25mg, 50mg, and 100mg. These options allow for tailored therapy depending on the patient's needs and the physician's directives.

The common starting dose for most adult men is 50mg, taken approximately one hour before sexual activity. However, it is crucial to adhere strictly to the recommended dosing intervals and not to take sildenafil more than once a day to avoid potential side effects.

Depending on individual response and tolerance, physicians may adjust the dose to a maximum of 100mg or reduce it to 25mg. The goal is to find the optimal balance between efficacy and tolerability.

To optimize effectiveness, take sildenafil up to 4 hours before sexual activity; sexual stimulation is necessary for the medication to work, as sildenafil does not induce an erection without sexual arousal.

Dosage and Strength for Pulmonary Hypertension

For the treatment of pulmonary arterial hypertension, sildenafil is prescribed in lower strengths, specifically 10mg and 20mg tablets. This lower dosing reflects the different therapeutic goals in managing this condition versus erectile dysfunction.

The standard adult dosage for pulmonary hypertension is 20mg taken three times a day, ensuring doses are evenly spaced to maintain steady drug levels in the body and optimize therapeutic effect.

In pediatric cases, dosages vary between 10mg and 20mg, also administered three times a day based on the child's weight. It is crucial to adhere to prescribed frequencies and not exceed three times daily.

How to Take Sildenafil Tablets

Swallow the tablets whole with a glass of water or juice. Avoid grapefruit juice, as it can interact with the medication and lead to increased side effects or decreased efficacy.

For best results in treating erectile dysfunction, it's recommended to take sildenafil on an empty stomach. This is because high-fat meals can delay the absorption of the medication, potentially affecting its effectiveness.

How to Take Liquid Sildenafil

Liquid sildenafil formulation is also available, where 1ml typically equals a 10mg tablet. Always refer to the specific medication label for accurate dosing, as liquid formulations may have different concentrations.

Liquid forms are usually prepared by a pharmacist, and patients should use the accompanying plastic syringe or spoon for dosage to ensure precision. Standard kitchen spoons should be avoided as they can lead to inaccurate dosing.

What to Do if You Forget a Dose

If you miss a dose and are treating pulmonary hypertension, take it as soon as you remember unless it’s nearly time for your next scheduled dose. In that case, skip the missed dose and resume your usual schedule to prevent overdose.

Never double up on doses to compensate for a missed dose. If you frequently forget doses, setting reminders or alarms may help you stick to your regimen and ensure consistent treatment.

If You Take Too Much Sildenafil

Overdosing on sildenafil can lead to adverse side effects and health complications, which can include serious cardiovascular events.

If you suspect an overdose, contact your healthcare provider immediately, especially if you experience any of the following symptoms:

  • Headaches
  • Dizziness
  • Indigestion
  • Blocked nose
  • Changes to your vision

Other Precautions

Before taking sildenafil, it is essential to inform your doctor about any other medications you are taking, especially nitrates or medications for high blood pressure, due to potential interactions that could lead to severe hypotension.

Inform your healthcare provider if you have any pre-existing health conditions, particularly heart-related issues, kidney problems, or a history of stroke. This background is crucial for proper risk assessment before commencing treatment.

Common Side Effects

Most patients tolerate sildenafil well. However, side effects may occur, including:

  • Headaches
  • Facial flushing
  • Nasal congestion
  • Upset stomach

If side effects persist or worsen, consult a healthcare professional for guidance. Monitoring is essential to ensure that any adverse effects are managed swiftly and effectively.

Page last reviewed: 2 March 2022
Next review due: 2 March 2025