Dapoxetine Online; Berkshire Orthopaedic Associates

Dapoxetine 30mg/60mg/90mg Tablets Online

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Dapoxetine, commonly branded as Priligy, is categorized as a Selective Serotonin Reuptake Inhibitor (SSRI), primarily prescribed for the management of erectile dysfunction, particularly for addressing the issue of premature ejaculation. This condition involves the inability to delay ejaculation during sexual intercourse, often resulting in distress for individuals affected. Dapoxetine is available in various dosages, represented by round tablets that come in distinct colors, varying according to their respective brand names.

Uses of Dapoxetine

This medication is specifically effective for treating premature ejaculation in men between the ages of 18 and 64, particularly those who present with the following symptoms:

• Persistent difficulty in controlling ejaculation, characterized by recurring instances of ejaculation occurring with minimal sexual stimulation shortly before, during, or after vaginal penetration, against the individual's desire.
• The occurrence of ejaculation within two minutes of vaginal penetration, indicating an intravaginal ejaculatory latency time of less than 2 minutes.
• A significant level of psychological distress stemming from premature ejaculation.

How Does Dapoxetine Work

Dapoxetine acts as an SSRI by inhibiting the serotonin transporter, which is pivotal in modulating ejaculatory signals. By preventing the reuptake of serotonin, the drug enhances serotonergic activity at the postsynaptic clefts, prolonging ejaculatory delay and providing better control over the ejaculation process.

Precautions

Prior to initiating Dapoxetine treatment, it is crucial to carefully review the associated precautions. If there are any doubts regarding the safety profile of this medication, consult a healthcare professional for personalized guidance. It is essential to notify your doctor of any known allergies to Dapoxetine or similar compounds. Additionally, disclose your medical history regarding:

• Pre-existing heart disorders, such as arrhythmias or heart failure;
• Blood clotting or bleeding issues;
• Episodes of fainting;
• Elevated eye pressure (glaucoma);
• Severe liver diseases;
• Kidney dysfunction;
• Seizure disorders;
• Mental health disorders like bipolar disorder, depression, or mania;
• Substance abuse including alcohol;
• Use of monoamine oxidase inhibitors (MAOIs) within the preceding two weeks.

Dapoxetine is contraindicated for individuals under 18 years, as well as for women who are pregnant or breastfeeding. Due to potential side effects such as dizziness and drowsiness, it is advisable to refrain from operating heavy machinery or driving until you understand how Dapoxetine affects you. Furthermore, alcohol consumption can exacerbate these side effects.

It is recommended to avoid grape juice within 24 hours prior to taking Dapoxetine, as this can lead to increased plasma levels of the drug, enhancing its effects and potential side effects.

Consumption of Dapoxetine should be reserved for those with a clinical diagnosis of erectile dysfunction, ensuring responsible usage.

Dapoxetine Dosage and Administration

The administration of Dapoxetine occurs orally, with or without food. To mitigate its bitter taste, it is essential to swallow the tablets whole with a sufficient amount of water. Utilizing Dapoxetine when necessary is crucial for maintaining its effectiveness.

The general recommended dosage is 30 mg taken approximately 1 to 3 hours prior to anticipated sexual activity. If the initial dosing is found to be inadequate yet well-tolerated, your healthcare provider might consider increasing the dose to 60 mg.

It is imperative not to utilize this medication daily or exceed the 30 mg daily limit, as this can significantly elevate the risk of adverse reactions.

Side Effects of Dapoxetine

Individuals taking Dapoxetine may experience a range of side effects, which can include but are not limited to:

• Headaches;
• Increased sweating;
• Anxiety;
• Dizziness;
• Blurred vision;
• Elevated blood pressure;
• Nervousness and confusion;
• Reduced libido;
• Irregular or rapid heartbeat;
• Unusual dreams;
• Ringing in the ears;
• Erection difficulties;
• Gastrointestinal issues such as diarrhea;
• Nausea and vomiting;
• General fatigue;
• Somnolence;
• Dry mouth.

Missed Dose and Overdose

Since this medication is intended for use as needed, the likelihood of missing a dose is minimal. However, users should refrain from self-adjusting their dosages without proper medical oversight due to the risk of overdose and the potential for severe side effects. In case of suspected overdose, immediate medical attention should be sought by calling emergency services or contacting a poison control center.

Interactions

Dapoxetine has potential interactions with various medications and health conditions. Notable drug interactions include:

• Acalabrutinib: The combination may heighten the risk of bleeding;
• Monoamine oxidase inhibitors such as Tranylcypromine and Moclobemide;
• Herbal remedies like St. John’s wort;
• Amino acid supplements such as Tryptophan;
• Various antidepressants including Sertraline, Amitriptyline, Paroxetine, Venlafaxine, Escitalopram, Nortriptyline, Doxepin, and Fluvoxamine;
• Antibiotics like Linezolid, Clarithromycin, Telithromycin, and Erythromycin;
• Fluconazole;
• Tramadol;
• Ketoconazole;
• Warfarin;
• Lithium;
• Ritonavir;
• Verapamil.

Regarding disease interactions, Dapoxetine may pose risks for:

• Individuals with glaucoma, as increased intraocular pressure can lead to severe visual disturbances;
• Individuals with compromised kidney function, since the drug is primarily eliminated through the kidneys and could lead to accumulation in those with renal impairment;
• Depressive disorders;
• Liver dysfunction.

Ingestion of grape juice alongside Dapoxetine can potentially intensify the drug's effects due to increased concentration and prolonged action in the bloodstream.

Storage

To ensure optimal effectiveness, Dapoxetine should be stored in a cool, dry location that is inaccessible to children and pets.