Dapoxetine Online; Berkshire Orthopaedic Associates

Dapoxetine 30mg/60mg/90mg Tablets Online

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Dapoxetine, commonly marketed as Priligy, is classified as a Selective Serotonin Reuptake Inhibitor (SSRI). This medication is predominantly prescribed to address erectile dysfunction, specifically in men who experience the complication of premature ejaculation, which occurs when ejaculation happens too swiftly during sexual relations. The formulation of Dapoxetine is typically in the form of round tablets, available in various colors, which differ based on the branding of the product.

Uses of Dapoxetine

The primary indication for Dapoxetine involves the management of premature ejaculation in males ranging from 18 to 64 years old, who are exhibiting the following clinical characteristics:

• Deficient control over ejaculation that manifests in persistent or recurrent instances of ejaculation occurring with minimal sexual excitement, either immediately before, during, or shortly after vaginal penetration, and against the individual's preference.
• An ejaculatory latency time of less than 2 minutes during vaginal penetration and stimulation, which is clinically termed as intravaginal ejaculatory latency time (IELT) of < 2 mins.
• Notable distress or discomfort arising from premature ejaculation.

How Does Dapoxetine Work

Dapoxetine operates as an SSRI by specifically blocking the serotonin transporter, thereby modulating the neurotransmitter serotonin that plays a crucial role in regulating ejaculatory response. The inhibition of serotonin reuptake extends the action duration of serotonin at the postsynaptic clefts. This pharmacological action not only prolongs the time taken to ejaculate but also fosters better control over the ejaculatory process, contributing to an enhanced sexual experience.

Precautions

It is imperative to meticulously review these precautionary measures prior to commencing treatment with this medication. Should you have any personal reservations regarding the safety profile of this medication, please do not hesitate to consult a healthcare professional for guidance.

Be sure to notify your healthcare provider if you have exhibited any allergic reactions to Dapoxetine or similar compounds. Furthermore, it is essential to inform your physician of your history regarding:

• Specific types of cardiovascular conditions (for instance, heart rhythm abnormalities or heart insufficiency);
• Blood coagulation or bleeding disorders;
• A tendency to experience fainting spells;
• Increased intraocular pressure or glaucoma;
• Moderate or severe hepatic impairment;
• Renal dysfunction;
• Seizure history;
• Existing mental health disorders such as mania, clinical depression, or bipolar disorder;
• History of alcohol abuse;
• Use of controlled substances or drugs abuse;
• Receiving treatment with monoamine oxidase inhibitors (MAOIs) within the previous two weeks.

Dapoxetine is contraindicated for individuals under the age of 18 and is not intended for use in females, especially those who are pregnant or breastfeeding.

Because this medication can induce dizziness, drowsiness, or fainting, it is advisable to refrain from operating heavy machinery or undertaking prolonged driving while on Dapoxetine therapy.

Moreover, consuming alcoholic beverages during Dapoxetine treatment may amplify feelings of dizziness and lethargy.

Additionally, it is prudent to avert the consumption of grape juice within 24 hours prior to the administration of Dapoxetine, as it may elevate the concentration of Dapoxetine hydrochloride in the bloodstream.

This medication should only be taken if you have been clinically diagnosed with erectile dysfunction.

Dapoxetine Dosage and Administration

Dapoxetine is designed for oral administration and can be ingested with food or on an empty stomach. It is crucial to swallow the tablets whole, with an ample amount of water, to minimize any unpleasant taste. Dapoxetine should be taken only as required.

The standard starting dose is 30 mg (one tablet), administered 1 to 3 hours before engaging in sexual activity. A healthcare provider may adjust your dosage to 60 mg if the initial amount proves to be inadequate and if you tolerate the increased dosage without adverse effects such as fainting.

It is critical that this medication is not consumed on a daily basis or in excess of 30 mg within a 24-hour timeframe, as doing so could significantly heighten the risk of serious side effects.

Side Effects of Dapoxetine

Dapoxetine may produce a range of side effects, including but not limited to:

• Headaches;
• Excessive perspiration;
• Heightened anxiety;
• Dizziness;
• Blurred vision;
• Elevated blood pressure;
• Nervousness and confusion;
• Decreased sexual desire;
• Palpitations or irregular heart rhythms;
• Unusual dreams;
• Auditory ringing;
• Issues with achieving an erection;
• Gastrointestinal disturbances, including diarrhea;
• Nausea and potential vomiting;
• Excessive fatigue;
• Increased sleepiness;
• Xerostomia (dry mouth).

Missed Dose and Overdose

Given that Dapoxetine is prescribed for use only when necessary, the likelihood of missing a dose is minimal. However, it is crucial not to increase your dosage without medical approval to prevent potential overdose and serious adverse effects. In the event of an overdose or suspected poisoning, contact emergency services or the poison control center immediately.

Interactions

It is important to note that Dapoxetine may interact with various medications and specific medical conditions. Some notable drug interactions include:

• Acalabrutinib (the concurrent use of Dapoxetine and Acalabrutinib escalates the risk of bleeding);
• Monoamine oxidase inhibitors, such as Tranylcypromine and Moclobemide;
• St. John's wort;
• Tryptophan;
• Antidepressants (including Sertraline, Amitriptyline, Paroxetine, Venlafaxine, Escitalopram, Nortriptyline, Doxepin, Fluvoxamine);
• Antibiotics like Linezolid, Clarithromycin, Telithromycin, and Erythromycin;
• Fluconazole;
• Tramadol;
• Ketoconazole;
• Warfarin;
• Lithium;
• Ritonavir;
• Verapamil.

Moreover, Dapoxetine interacts with several medical conditions, including:

• Glaucoma, a condition characterized by increased intraocular pressure. Caution is advised when prescribing Dapoxetine to individuals with glaucoma to mitigate potential side effects such as blurred vision or even vision loss.
• Impaired renal function. Since Dapoxetine is eliminated through the kidneys, it should be used with caution in those with mild to moderate kidney impairment to prevent accumulation in the bloodstream.
• Depression;
• Liver dysfunction;

Consuming Dapoxetine in conjunction with grape juice may elevate the concentration of the drug in the blood beyond desired levels.

Storage

Dapoxetine must be stored in a cool, dry environment, securely out of reach of children and pets to prevent accidental ingestion.